From Chapter 4:
We know also that the Roundhead soldiers smoked in circumstances that did them no credit. In the account of the trial of Charles I, written by Dr. George Bates, principal physician to his Majesty, and to Charles II also, we read that when the sentence of the Court presided over by Bradshaw, condemning the King "to death by severing his Head from his Body," had been read, the soldiers treated the fallen monarch with great indignity and barbarity. They spat on his clothes as he passed by, and even in his face; and they "blew the smoak of tobacco, a thing which they knew his Majesty hated, in his sacred mouth, throwing their broken Pipes in his way as he passed along."

From Chapter 5:
The belief in the prophylactic power of tobacco was, however, very generally held. When Mr. Samuel Pepys on June 7, 1665, for the first time saw several houses marked with the ominous red cross, and the words "Lord, have mercy upon us" chalked upon the doors, he felt so ill at ease that he was obliged to buy some roll tobacco to smell and chew. There is nothing to show that Pepys even smoked, which considering his proficiency in the arts of good-fellowship, is perhaps a little surprising. Defoe, in his fictitious but graphic "Journal of the Plague Year in London," says that the sexton of one of the London parishes, who personally handled a large number of the victims, never had the distemper at all, but lived about twenty years after it, and was sexton of the parish to the time of his death. This man, according to Defoe, "never used any preservative against the infection other than holding garlic and rue in his mouth, and smoking tobacco."