From Chapter 1:
Wherever Raleigh is known to have lived or lodged we are sure to find the tradition flourishing that there he smoked his first pipe. The assertion has been made of his birthplace, Hayes Barton, although it is very doubtful if he ever visited the place after his parents left it, some years before their son had become acquainted with tobacco; and also with more plausibility of his home at Youghal, in the south of Ireland. Froude, in one of his "Short Studies," quotes a legend to the effect that Raleigh smoked on a rock below the Manor House of Greenaway, on the River Dart, which was the home of the first husband of Katherine Champernowne, afterwards Raleigh's wife; and Devonshire guide-books have adopted the story.

From Chapter Chapter 8:
Cowper then goes on to attack tobacco in lines which show how unpopular smoking at that date was with ladies, and which have since often been quoted by anti-tobacconists with grateful appreciation:

Pernicious weed! whose scent the fair annoys,
Unfriendly to society's chief joys,
Thy worst effect is banishing for hours
The sex whose presence civilizes ours;
Thou art indeed the drug a gardener wants,
To poison vermin that infest his plants,
But are we so to wit and beauty blind,
As to despise the glory of our kind,
And show the softest minds and fairest forms
As little mercy as the grubs and worms?

Notwithstanding this "satiric wipe," it is not likely that Cowper would have had much sympathy with John Wesley, who, in his detestation of what had been his father's solace at Epworth, forbade his preachers either to smoke or to take snuff.